The company was restructured during the second wave of nationalization by the communists, and brought under government control. The RTN project continues under SPOFA as state Factory 15 Eko.

The RTN transitions into a new phase with the founding of the Institute for Medicinal Plant Research.

Retisin, Lyastin, Floristen, and Silexil successfully completed clinical trials and entered large-scale manufacturing, intended as standard tools in national public health.

RTN preparations are quietly shelved, despite clinical success, public support, and physician advocacy. A new wave of pharmacology prefer synthetics - cleaner on paper, simpler to patent, easier to mass-produce.

Long after Retisin vanished from hospitals, two of its original architects, Dr. Bedřich Doležel and MUDr. Gabriel Urbánek, refused to let it die. They patented a method for producing tissue-based preparations under the University of Chemistry and Technology in Prague. The result was a civilian echo of the original Retisin. Dietary supplement named Juvenil, later Imuregen, was manufactured in partnership with the state-run Jednota Hronov collective.

Dr. Bedřich Doležel remained at the university. Jednota Hronov, once a state-run manufacturing collective, slipped into private hands and despite nearing bankruptcy.

Two of his younger academic colleagues saw opportunity and founded Juwima, later branded Juwital and Juwim. Around the same time, Bob Rakušan, son of Dr. Bohumír Rakušan, tried to resurrect his father’s original RTN formulas with their help. But recreating RTN wasn’t like spinning up another supplement. Juvenil/Imuregen aka Juwim lived on. RTN did not.

The former State Glass Research Institute (SVÚS, now part of Nuraxpharm Group), once responsible for producing Imuregen colony under Dr. Doležel’s supervision for Jednota Hronov began using Juwim in a new product called Preventan. They launched their own brand ProteQuine later.